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NOTCH4 Recombinant Rabbit mAb (bsm-61337R)  
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產品編號 bsm-61337R
英文名稱 NOTCH4 Recombinant Rabbit mAb
中文名稱 跨膜蛋白NOTCH4配體重組兔單抗
別    名 NOTC4; hNotch4; INT3; Notch homolog 4.  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號
交叉反應 Human,Mouse
產品應用 WB=1:1000-1:2000,Flow-Cyt=1:20-1:100
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 210 kDa
檢測分子量 230
性    狀 Liquid
免 疫 原 A synthesized peptide derived from human Notch 4: 1950-2003 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
保存條件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system.

SWISS:
Q99466

Gene ID:
4855

產品圖片
Western blot analysis of Mouse lung lysate. Using NOTCH4 (bsm-61337R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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