| 產(chǎn)品編號(hào) | bsm-61715R |
| 英文名稱 | Plexin A1 Recombinant Rabbit mAb |
| 中文名稱 | 神經(jīng)叢蛋白A1重組兔單抗 |
| 別 名 | NOV; NOVP; Plexin-A1; Plexin1; PlexinA1; PLXN1; Plxna1. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 8C6 |
| 交叉反應(yīng) | Rat (predicted: Human,Mouse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-1:2000,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 211 kDa |
| 檢測分子量 | 211 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Plexin A1: 100-180/1896 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. SWISS: Q9UIW2 Gene ID: 5361 Plexins是一種單途徑、具有多向潛在功能的跨膜蛋白，為Sema-phorins（神經(jīng)信號(hào)蛋白）家族的受體,PlexinA1蛋白主要定位于細(xì)胞質(zhì)和細(xì)胞膜，Semaphorins的很多重要的生理作用均是通過Plexins信號(hào)傳導(dǎo)來發(fā)揮作用的。PlexinA1在神經(jīng)系統(tǒng)形成、心血管生成、胚胎發(fā)生和免疫反應(yīng)等方面發(fā)揮重要作用。 |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with Plexin A1 monoclonal antibody, unconjugated (bsm-61715R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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