產(chǎn)品編號(hào) | bsm-61841R |
英文名稱 | PDE4D Recombinant Rabbit mAb |
中文名稱 | 磷酸二酯酶4D重組兔單抗 |
別 名 | DPDE3; HSPDE4D; PDE43; Pde4d; PDE4DN2; STRK1. |
抗體來源 | Rabbit |
克隆類型 | Recombinant |
克 隆 號(hào) | |
交叉反應(yīng) | Human |
產(chǎn)品應(yīng)用 | WB=1:500-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 91 kDa |
檢測(cè)分子量 | 91 |
性 狀 | Liquid |
免 疫 原 | A synthesized peptide derived from human PDE4D: 650-809/809 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. SWISS: Q08499 Gene ID: 5144 經(jīng)研究發(fā)現(xiàn)磷酸二酯酶(PDE4D)基因可使缺血性卒中的危險(xiǎn)性增高,使人患動(dòng)脈粥樣硬化及中風(fēng)的風(fēng)險(xiǎn)性增高,有可能是通過影響動(dòng)脈內(nèi)平滑肌細(xì)胞的增生和擴(kuò)散相關(guān)。目前,PDE4D基因的變化機(jī)理并不是完全清楚,有待進(jìn)一步研究 |
產(chǎn)品圖片 | |