| 產(chǎn)品編號(hào) | bsm-62287R |
| 英文名稱 | FRA1 Recombinant Rabbit mAb |
| 中文名稱 | FRA-1蛋白重組兔單抗 |
| 別 名 | FOS L1; FOS like antigen 1; FOSL1; FRA 1. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 8C7 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:500-1:2000,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 29 kDa |
| 檢測(cè)分子量 | 39 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human FRA1: 130-210/271 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. SWISS: P15407 Gene ID: 8061 FOSL1蛋白對(duì)細(xì)胞因子、生長(zhǎng)因子、感染或致癌刺激等生理或病理信號(hào)發(fā)生應(yīng)答,調(diào)節(jié)基因的轉(zhuǎn)錄, 參與細(xì)胞的增殖、分化等過(guò)程。 FOSL1在腫瘤形成及發(fā)展過(guò)程中, 通過(guò)促進(jìn)細(xì)胞增殖、抑制分化、促進(jìn)腫瘤細(xì)胞的侵襲和轉(zhuǎn)移等過(guò)程發(fā)揮作用。 |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with FRA1 monoclonal antibody, unconjugated (bsm-62287R) at 1:2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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