| 產(chǎn)品編號 | bsm-62339R |
| 英文名稱 | Neurocan Recombinant Rabbit mAb |
| 中文名稱 | 神經(jīng)粘蛋白重組兔單抗 |
| 別 名 | Cspg3; Ncan; NEUR; Neurocan core protein. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,IP=1:20-50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 143 kDa |
| 檢測分子量 | 130270 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Neurocan: 2-51/1321 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid. SWISS: O14594 Gene ID: 1463 神經(jīng)生物學(xué)相關(guān)蛋白（Neurobiology） 神經(jīng)粘蛋白(Neurocan)是由神經(jīng)元分泌的特異性蛋白質(zhì),廣泛分布于神經(jīng)系統(tǒng),可與神經(jīng)元細(xì)胞膜上特異性受體神經(jīng)粘附分子和神經(jīng)元膠質(zhì)細(xì)胞黏附分子結(jié)合,調(diào)節(jié)細(xì)胞連接,影響軸突生長.而在中樞神經(jīng)系統(tǒng)損傷后,Neurocan的表達(dá)增加,并抑制軸突生長.Neurocan在中樞神經(jīng)系統(tǒng)的形成和損傷后的修復(fù)都扮演著重要的角色. |
| 產(chǎn)品圖片 |
Western blot analysis of Fetal brain cell lysate. Using Neurocan (bsm-62339R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Neurocan Monoclonal Antibody, Unconjugated (bsm-62339R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
(Negative control) Paraformaldehyde-fixed, paraffin embedded Human Skeletal muscle; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Neurocan Monoclonal Antibody, Unconjugated (bsm-62339R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
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