| 產(chǎn)品編號(hào) | bsm-62474R |
| 英文名稱 | P73 Recombinant Rabbit mAb |
| 中文名稱 | 腫瘤蛋白P73重組兔單抗 |
| 別 名 | p53-like transcription factor; p53-related protein; P73 alpha protein; p73-alpha; TP73; TRP73; Tumor protein p73. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 70 kDa |
| 檢測(cè)分子量 | 70 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human p73: 55-80 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. Is an activator of FOXJ1 expression. It is an essential factor for the positive regulation of lung ciliated cell differentiation. SWISS: O15350 Gene ID: 7161 P73是p53基因家族的第一個(gè)成員p53基因是一個(gè)經(jīng)典的抑癌基因,與p53在結(jié)構(gòu)和功能方面具有很高的相似性。 |
| 產(chǎn)品圖片 |
Western blot analysis of HeLa cell lysate. Using P73 (bsm-62474R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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