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IL-4I1 Rabbit pAb (bs-6841R)  
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產品編號 bs-6841R
英文名稱 IL-4I1 Rabbit pAb
中文名稱 白細胞介素4誘導蛋白1抗體
別    名 IL4I1; hFIG1; IL4 induced protein 1; IL-4 induced protein 1; Interleukin 4 induced protein 1; LAAO; FIG 1; Fig 1 protein; FIG1; Fig1 protein; hFIG 1; hFIG1; IL4-induced protein 1; Interleukin 4 induced 1; Interleukin four induced 1; Interleukin-4-induced protein 1; L amino acid oxidase; L-amino-acid oxidase; LAAO; LAO; Protein Fig 1; Protein Fig-1; Protein Fig1; OXLA_HUMAN.  
研究領域 細胞生物  細胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse,Rat (predicted: Human,Pig,Sheep,Dog)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 61 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IL-4I1: 51-160/567 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].

Function:
Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation (By similarity).

Subcellular Location:
Isoform 1: Lysosome (By similarity).
Isoform 2: Lysosome (By similarity).

Tissue Specificity:
Isoform 1 is primarily found in immune tissues.

Similarity:
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

SWISS:
Q96RQ9

Gene ID:
259307

Database links:

Entrez Gene: 259307 Human

Entrez Gene: 14204 Mouse

Omim: 609742 Human

SwissProt: Q1WMJ3 Human

SwissProt: Q96RQ9 Human

SwissProt: O09046 Mouse

Unigene: 27567 Mouse



產品圖片
Paraformaldehyde-fixed, paraffin embedded (rat spleen); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IL-4I1) Polyclonal Antibody, Unconjugated (bs-6841R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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