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SLC2A4RG Rabbit pAb (bs-9457R)  
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產(chǎn)品編號 bs-9457R
英文名稱 SLC2A4RG Rabbit pAb
中文名稱 葡萄糖轉(zhuǎn)運蛋白4增強因子抗體
別    名 GEF; GLUT4 enhancer factor; HDBP 1; HDBP-1; HDBP1; Huntington disease gene regulatory region binding protein 1; Huntington disease gene regulatory region-binding protein 1; S2A4R_HUMAN; Si 1 2 19; Si 1 2; SLC2A4 regulator; SLC2A4RG; Zinc finger protein 2 5 Glut4 enhancer factor.  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human,Mouse (predicted: Sheep,Cow)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 41 kDa
檢測分子量
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC2A4RG: 301-387/387 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. The encoded protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene. [provided by RefSeq, Jul 2008].

Function:
Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence 5'-GCCGGCG-3'.

Subunit:
Interacts with MEF2A.

Subcellular Location:
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus.

Tissue Specificity:
According to PubMed:14630949, expressed in heart, skeletal muscle, liver, kidney and pancreas; undetectable in lung, placenta or brain. According to PubMed:14625278, ubiquitously expressed, with lowest expression in brain and ileum.

Similarity:
Contains 1 C2H2-type zinc finger.

SWISS:
Q9NR83

Gene ID:
56731

Database links:

Entrez Gene: 56731 Human

Omim: 609493 Human

SwissProt: Q9NR83 Human

Unigene: 435126 Human



產(chǎn)品圖片
Sample: Lane 1: Mouse Heart tissue lysates Lane 2: Mouse Muscle tissue lysates Primary: Anti-SLC2A4RG (bs-9457R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kDa Observed band size: 41 kDa
Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti- SLC2A4RG (bs-9457R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kD Observed band size: 41 kD
Paraformaldehyde-fixed, paraffin embedded (human kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC2A4RG) Polyclonal Antibody, Unconjugated (bs-9457R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (human skeletal muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC2A4RG) Polyclonal Antibody, Unconjugated (bs-9457R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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