| 產(chǎn)品編號 | bs-8865R | 
| 英文名稱 | CD28 Rabbit pAb | 
| 中文名稱 | CD28抗體 | 
| 別 名 | CD 28; CD28 antigen; CD28 molecule; MGC138290; T cell antigen CD28; T cell specific surface glycoprotein; T cell specific surface glycoprotein CD28; Tp44; CD28_HUMAN. | 
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 Specific References  (3)     |     bs-8865R has been referenced in 3 publications. 
[IF=3.549] Jingjing Li. et al. Circular RNA hsa_circ_0068252 functions in cisplatin resistance and immune response via miR-1304-5p/PD-L1 axis in non-small cell lung cancer. CHEMOTHERAPY. ;:  IA ;  Human.   
[IF=3.098] Junli Zhang. et al. KCNQ1OT1 contributes to sorafenib resistance and programmed death?ligand?1?mediated immune escape via sponging miR?506 in hepatocellular carcinoma cells. Int J Mol Med. 2020 Nov;46(5):1794-1804  ELISA ;  Human.   
[IF=3.057] Song et al. Forsythoside A Inhibits BVDV Replication via TRAF2-Dependent CD28-4-1BB Signaling in Bovine PBMCs. (2016) PLoS.On. 11:e0162791  WB ;  Cow.   
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| 研究領(lǐng)域 | 細(xì)胞生物 干細(xì)胞 細(xì)胞膜受體 細(xì)胞粘附分子 細(xì)胞表面分子 淋巴細(xì)胞 t-淋巴細(xì)胞 b-淋巴細(xì)胞 | 
| 抗體來源 | Rabbit | 
| 克隆類型 | Polyclonal | 
| 克 隆 號 | |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat) | 
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.  | 
| 理論分子量 | 25 kDa | 
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 | 
| 性 狀 | Liquid | 
| 濃 度 | 1mg/ml | 
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CD28: 19-120/220 <Extracellular> | 
| 亞 型 | IgG | 
| 純化方法 | affinity purified by Protein A | 
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. | 
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. | 
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. | 
| PubMed | PubMed | 
| 產(chǎn)品介紹 | 
The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011] Function: Possibly involved in T-cell activation. Subunit: Homodimer; disulfide-linked. Interacts with DUSP14. Binds to CD80/B7-1 and CD86/B7-2/B70. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in T-cells and plasma cells, but not in less mature B-cells. Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. SWISS: P10747 Gene ID: 940 Database links: Entrez Gene: 940 Human Entrez Gene: 12487 Mouse Omim: 186760 Human SwissProt: P10747 Human SwissProt: P31041 Mouse SwissProt: P42069 Rabbit Unigene: 591629 Human Unigene: 255003 Mouse  |