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ZNF93 Rabbit pAb (bs-13558R)  
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產(chǎn)品編號(hào) bs-13558R
英文名稱 ZNF93 Rabbit pAb
中文名稱 鋅指蛋白93抗體
別    名 FLJ12488; HPF34; HTF34; TF34; Zinc finger protein 505; Zinc finger protein 93(HTF34); Zinc finger protein 93; Zinc finger protein HTF34; ZNF505; ZNF93; ZNF93_HUMAN.  
Specific References  (1)     |     bs-13558R has been referenced in 1 publications.
[IF=0.252] Xiao-Xiao Cui. et al. High expression of ZNF93 promotes proliferation and migration of ovarian cancer cells and relates to poor prognosis. Int J Clin Exp Patho. 2020; 13(5): 944–953  IHC ;  Human.  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 71 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZBT24/ZNF45: 521-620/620 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Transcription factor specifically required to repress long interspersed nuclear element 1 (L1) retrotransposons: recognizes and binds L1 sequences and repress their expression by recruiting a repressive complex containing TRIM28/KAP1 (PubMed:25274305). Not able to repress expression of all subtypes of L1 elements. Binds to the 5 end of L1PA4, L1PA5 and L1PA6 subtypes, and some L1PA3 subtypes. Does not bind to L1PA7 or older subtypes nor at the most recently evolved L1PA2 and L1Hs. 50% of L1PA3 elements have lost the ZNF93-binding site, explaining why ZNF93 is not able to repress their expression (PubMed:25274305).

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus.

DISEASE:
Expressed early during embryonic development.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 17 C2H2-type zinc fingers.
Contains 1 KRAB domain.

SWISS:
P35789

Gene ID:
81931

Database links:

Entrez Gene: 81931 Human

Omim: 603975 Human

SwissProt: P35789 Human

Unigene: 301059 Human

Unigene: 723768 Human



產(chǎn)品圖片
Sample: HL-60 (human)cell Lysate at 40 ug MCF-7 (human)cell Lysate at 40 ug Primary: Anti-ZNF93 (bs-13558R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 71 kD Observed band size: 71 kD
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