產(chǎn)品編號 | bs-16167R |
英文名稱 | FOXJ3 Rabbit pAb |
中文名稱 | FOXJ3蛋白抗體 |
別 名 | Forkhead box J3; Forkhead box protein J3; FOXJ3; FOXJ3_HUMAN; KIAA1041; MGC165036; MGC176686. |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號 | |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 69 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FOXJ3: 121-220/622 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
FOXJ3 (forkhead box protein J3) is a 622 amino acid protein encoded by the human gene FOXJ3. FOXJ3, having one forkhead DNA-binding domain, is a novel forkhead factor and, as such, belongs to the forkhead protein family. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. Forkhead factors are known to play important roles both during development and in adults. FOXJ3 is expressed in neuroectoderm, in neural crest, and in many structures derived from neural crest cells, such as facioacoustic, trigeminal and dorsal root ganglia. Stripes of FOXJ3 expression appear in the location of myotomes and expand ventrally in a pattern similar to the developing body wall musculature. Developing limbs have a complex pattern of FOXJ3 expression that at E12.5 colocalizes with the condensed mesenchyme of the skeletal primordia. Subcellular Location: Nucleus. Similarity: Contains 1 fork-head DNA-binding domain. SWISS: Q9UPW0 Gene ID: 22887 Database links: Entrez Gene: 22887 Human Entrez Gene: 230700 Mouse SwissProt: Q9UPW0 Human SwissProt: Q8BUR3 Mouse Unigene: 26023 Human Unigene: 259227 Mouse Unigene: 202994 Rat |
產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FOXJ3) Polyclonal Antibody, Unconjugated (bs-16167R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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