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GTPBP1 Rabbit pAb (bs-16365R)  
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產(chǎn)品編號(hào) bs-16365R
英文名稱 GTPBP1 Rabbit pAb
中文名稱 G蛋白結(jié)合蛋白1抗體
別    名 G protein 1; GP 1; GTPB1_HUMAN; GP1; GTP binding protein 1.  
研究領(lǐng)域 信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Rat (predicted: Human,Mouse,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 72 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GTPBP1: 501-600/669 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [provided by RefSeq, Jul 2008]

Function:
The GTPBP1 gene is upregulated by interferon gamma and the protein is a member of the AGP11/GTPBP1 family of GTP binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. This gene is upregulated by interferon gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype.

Subunit:
Interacts with EXOSC2/RRP4, EXOSC3/RRP40, EXOSC5/RRP46, HNRNPD, HNRNPR and SYNCRIP. Identified in a complex with AANAT mRNA, but does not bind mRNA by itself (By similarity).

Subcellular Location:
Cytoplasm (By similarity).

Similarity:
Belongs to the GTPBP1 GTP-binding protein family.

SWISS:
O00178

Gene ID:
9567

Database links:

Entrez Gene: 9567 Human

Entrez Gene: 14904 Mouse

Entrez Gene: 300077 Rat

Omim: 602245 Human

SwissProt: O00178 Human

SwissProt: O08582 Mouse



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GTPBP1) Polyclonal Antibody, Unconjugated (bs-16365R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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