| 產(chǎn)品編號(hào) | bs-17146R |
| 英文名稱(chēng) | TRMT6 Rabbit pAb |
| 中文名稱(chēng) | TRMT6蛋白抗體 |
| 別 名 | KIAA1153; Adenine N; CGI 09; CGI09; GCD10; Gcd10p; KIAA1153; MGC5029; TRM6; TRM6_HUMAN; trmt6; tRNA(adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6; tRNA methyltransferase 6; tRNA methyltransferase 6 homolog(S. cerevisiae); tRNA(m1A58)-methyltransferase subunit TRM6; tRNA(m1A58)MTase subunit TRM6. |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 56 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TRMT6: 121-220/497 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Function: Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Subunit: tRNA (adenine-N(1)-)-methyltransferase is a heterodimer of TRM6 and TRM61. Subcellular Location: Nucleus. Tissue Specificity: Expressed in brain, liver, testis and ovary. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the TRM6/GCD10 family. SWISS: Q9UJA5 Gene ID: 51605 Database links: Entrez Gene: 51605 Human SwissProt: Q9UJA5 Human Unigene: 128791 Human |
| 產(chǎn)品圖片 |
Sample:Liver (Mouse)Lysate at 40 ug
Primary: Anti-TRMT6(bs-17146R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 56kD
Observed band size: 56kD
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