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INTS5 Rabbit pAb (bs-18179R)  
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產(chǎn)品編號 bs-18179R
英文名稱 INTS5 Rabbit pAb
中文名稱 INTS5蛋白抗體
別    名 1110055N21Rik; INT5; integrator complex subunit 5; KIAA1698; mKIAA1698; RGD1309370.  
研究領域 細胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse,Chimpanzee,Ferret,Rhesus monkey,Gorilla,Chinese Hamster)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 108 kDa
檢測分子量
細胞定位 細胞核 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human INTS5: 901-1019/1019 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 INTS5 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]

Function:
INTS5 is a subunit of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.

Subcellular Location:
Nucleus. Membrane; Multi pass membrane protein.

SWISS:
Q6P9B9

Gene ID:
80789

Database links:

Entrez Gene: 80789 Human

Entrez Gene: 109077 Mouse

Omim: 611349 Human

SwissProt: Q6P9B9 Human

SwissProt: Q8CHT3 Mouse



產(chǎn)品圖片
Sample: U87mg(Human) Cell Lysate at 30 ug Primary: Anti-INTS5 (bs-18179R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 108 kD Observed band size: 108 kD
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