產(chǎn)品編號(hào) | bs-18638R |
英文名稱 | MAK3/C14orf35 Rabbit pAb |
中文名稱 | 14號(hào)染色體開放閱框35抗體 |
別 名 | C14orf35; Chromosome 14 open reading frame 35; FLJ35355; MAK 3; Mak3p; MGC141884; MGC141885; N acetyltransferase 12(GCN5 related putative); N acetyltransferase 12; N acetyltransferase MAK3 homolog; NAT12; Putative N acetyltransferase. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號(hào) | |
交叉反應(yīng) | Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 39 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MAK3/C14orf35: 251-350/362 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
MAK3 belongs to the acetyltransferase family, MAK3 subfamily. It contains one N-acetyltransferase domain. It is a probable N-acetyltransferase. Function: Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. Necessary for the lysosomal localization and function of ARL8B sugeesting that ARL8B is a NatC substrate. Subunit: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30. Subcellular Location: Cytoplasmic Similarity: Belongs to the acetyltransferase family. MAK3 subfamily. Contains 1 N-acetyltransferase domain. SWISS: Q147X3 Gene ID: 122830 Database links: Entrez Gene: 122830 Human Entrez Gene: 70646 Mouse SwissProt: Q147X3 Human SwissProt: Q8CES0 Mouse Unigene: 165465 Human Unigene: 275688 Mouse Unigene: 15205 Rat |
產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (C14orf35) Polyclonal Antibody, Unconjugated (bs-18638R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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