產(chǎn)品編號(hào) | bs-18852R |
英文名稱 | METTL7A Rabbit pAb |
中文名稱 | 甲基化樣蛋白7A抗體 |
別 名 | AAM B; AAMB; DKFZP586A0522; MET7A_HUMAN; Methyltransferase like 7A; Methyltransferase-like protein 7A; METTL 7A; METTL7A; METTL7A methlytransferase like 7A; Protein AAM-B; Protein AAMB. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號(hào) | |
交叉反應(yīng) | Human (predicted: Mouse,Rat) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 25 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human METTL7A: 161-244/244 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
METTL7A is a 244 amino acid protein that is thought to function as a methyltransferase and is encoded by a gene which maps to chromosome 12. Encoding over 1,100 genes, chromosome 12 comprises nearly 4.5% of the human genome and is associated with a number of skeletal deformaties, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to both a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and a natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Additionally, Trisomy 12p (three copies of the p arm of chromosome 12) leads to facial developmental defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism. Function: Probable methyltransferase. Subcellular Location: Lipid droplet. Endoplasmic reticulum. Membrane. Similarity: Belongs to the methyltransferase superfamily. SWISS: Q9H8H3 Gene ID: 25840 Database links: Entrez Gene: 25840 Human Entrez Gene: 70152 Mouse SwissProt: Q9H8H3 Human Unigene: 725674 Human Unigene: 728181 Human |
產(chǎn)品圖片 | |