| 產(chǎn)品編號(hào) | bs-19224R |
| 英文名稱 | NFKBIL1 Rabbit pAb |
| 中文名稱 | 核因子κB抑制蛋白樣蛋白1抗體 |
| 別 名 | I-kappa-B-like protein; IkappaBL; IKBL; IKBL1_HUMAN; Inhibitor of kappa B-like protein; LST1; NF-kappa-B inhibitor-like protein 1; NFKBIL; Nfkbil1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Rat (predicted: Human,Mouse,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 43 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NFKBIL1: 81-180/381 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a divergent member of the I-kappa-B family of proteins. Its function has not been determined. The gene lies within the major histocompatibility complex (MHC) class I region on chromosome 6. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009] Function: May be a negative regulator of NF-kappa-B activation. Tissue Specificity: Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes. DISEASE: Defects in NFKBIL1 are a cause of susceptibility to rheumatoid arthritis (RA) [MIM:180300]. It is a systemic inflammatory disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Similarity: Contains 2 ANK repeats. SWISS: Q9UBC1 Gene ID: 4795 Database links: Entrez Gene: 4795 Human Entrez Gene: 18038 Mouse Omim: 601022 Human SwissProt: Q9UBC1 Human SwissProt: O88995 Mouse Unigene: 2764 Human Unigene: 300795 Mouse Unigene: 38632 Rat |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NFKBIL1) Polyclonal Antibody, Unconjugated (bs-19224R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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