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QTRT1 Rabbit pAb (bs-19699R)  
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產(chǎn)品編號(hào) bs-19699R
英文名稱 QTRT1 Rabbit pAb
中文名稱 鳥嘌呤插入酶QTRT1抗體
別    名 FP3235; Guanine insertion enzyme; qtrt1; Queuine tRNA ribosyltransferase 1; Queuine tRNA ribosyltransferase; Queuine tRNA-ribosyltransferase; TGT; TGT, 43 KD subunit; TGT, catalytic subunit; TGT_HUMAN; TGUT; tRNA guanine transglycosylase; tRNA-guanine transglycosylase.  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Mouse (predicted: Human,Rat,GuineaPig)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 44 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human QTRT1: 201-300/403 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Feb 2012]

Function:
Interacts with QTRTD1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

Subcellular Location:
Cytoplasm. Mitochondrion. Nucleus. Weakly associates with mitochondria, possibly via QTRTD1.

Similarity:
Belongs to the queuine tRNA-ribosyltransferase family.

SWISS:
Q9BXR0

Gene ID:
81890

Database links:

Entrez Gene: 476711 Dog

Entrez Gene: 81890 Human

Entrez Gene: 60507 Mouse

Entrez Gene: 64016 Rat

Entrez Gene: 393985 Zebrafish

Omim: 609615 Human

SwissProt: Q9BXR0 Human

SwissProt: Q9JMA2 Mouse

SwissProt: Q4QR99 Rat

SwissProt: Q7SYK1 Zebrafish

Unigene: 631638 Human

Unigene: 436579 Mouse

Unigene: 53858 Rat

Unigene: 9747 Zebrafish



產(chǎn)品圖片
Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-QTRT1 (bs-19699R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44 kD Observed band size: 48 kD
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