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p66 alpha/GATAD2A Rabbit pAb (bs-21072R)  
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產(chǎn)品編號(hào) bs-21072R
英文名稱 p66 alpha/GATAD2A Rabbit pAb
中文名稱 p66 α蛋白抗體
別    名 FLJ20085; FLJ21017; GATA zinc finger domain containing 2A; GATA zinc finger domain containing protein 2A; GATA zinc finger domain-containing protein 2A; GATAD2A; Hp66 alpha; Hp66alpha; OTTHUMP00000201911; OTTHUMP00000201912; P66 alpha; P66A_HUMAN; p66alpha; Transcriptional repressor p66 alpha; Transcriptional repressor p66-alpha; Transcriptional repressor p66alpha.  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Mouse (predicted: Human)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 68 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human p66 alpha: 151-250/633 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 GATAD2A (GATA Zinc Finger Domain Containing 2A) is a Protein Coding gene. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Development NOTCH1-mediated pathway for NF-KB activity modulation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein binding, bridging. An important paralog of this gene is GATAD2B.

Function:
Transcriptional repressor.

Subcellular Location:
Nucleus speckle.

Tissue Specificity:
Ubiquitous, both in fetal and adult tissues.

Similarity:
Contains 1 GATA-type zinc finger.

SWISS:
Q86YP4

Gene ID:
54815

Database links:

Entrez Gene: 508384 Cow

Entrez Gene: 54815 Human

Entrez Gene: 234366 Mouse

Entrez Gene: 290669 Rat

SwissProt: Q86YP4 Human

SwissProt: Q8CHY6 Mouse

Unigene: 118964 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (p66 alpha) Polyclonal Antibody, Unconjugated (bs-21072R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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