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SFRS17A Rabbit pAb (bs-21110R)  
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產(chǎn)品編號(hào) bs-21110R
英文名稱 SFRS17A Rabbit pAb
中文名稱 富含精氨酸/絲氨酸剪切因子17A抗體
別    名 721P; A kinase anchor protein 17A; A-kinase anchor protein 17A; AK17A_HUMAN; AKAP 17A; AKAP-17A; AKAP17A; arginine/serine-rich 17A; B lymphocyte antigen; B lymphocyte surface antigen; B-lymphocyte antigen; CCDC133; PRKA17A; Protein kinase A anchoring protein 17A; Protein kinase A-anchoring protein 17A; Protein XE7; Pseudoautosomal gene XE7; SFRS 17A; Splicing factor; Splicing factor arginine/serine rich 17A; XE 7; XE7.  
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 81 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SFRS17A: 501-600/695 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010]

Function:
Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.

Subunit:
Contains 1 RRM (RNA recognition motif) domain.

Subcellular Location:
Nucleus speckle.

Tissue Specificity:
Widely expressed. Found in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Expressed in activated B-cells and placenta. Expressed in all cell lines tested including Jurkat TAg, U937 and HEK293 cells.

SWISS:
Q02040

Gene ID:
8227

Database links:

Entrez Gene: 8227 Human

Omim: 312095 Human

SwissProt: Q02040 Human

Unigene: 522572 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Human kidney tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SFRS17A) Polyclonal Antibody, Unconjugated (bs-21110R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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