| 產(chǎn)品編號 | bsm-60261M |
| 英文名稱 | HDAC8 Mouse mAb |
| 中文名稱 | |
| 抗體來源 | Mouse |
| 克隆類型 | Monoclonal |
| 克 隆 號 | A6A2 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 亞 型 | IgG1, Kappa |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | 負(fù)責(zé)核心組蛋白（H2A、H2B、H3和H4）N端賴氨酸殘基的脫乙酰。組蛋白去乙酰化為表觀遺傳抑制提供了一個標(biāo)簽，在轉(zhuǎn)錄調(diào)控、細(xì)胞周期進(jìn)展和發(fā)育事件中起著重要作用。組蛋白脫乙酰基酶通過形成大的多蛋白復(fù)合物起作用。也參與粘蛋白復(fù)合物蛋白SMC3的脫乙酰化，調(diào)節(jié)染色質(zhì)中粘蛋白復(fù)合物的釋放?？赡茉谄交〖?xì)胞收縮中起作用。 |
| 產(chǎn)品圖片 |
Blocking buffer: 5% NFDM/TBST
Primary ab dilution: 1:1000
Primary ab incubation condition: 2 hours at room temperature
Lysate: HeLa, MCF-7, HepG2, A549, Daudi
Protein loading quantity: 20 μg
Exposure time: 60 s
Predicted MW: 40 kDa
Observed MW: 40 kDa
|
