| 產(chǎn)品編號(hào) | bsm-54066R |
| 英文名稱 | PLGF Recombinant Rabbit mAb |
| 中文名稱 | 胎盤生長(zhǎng)因子重組兔單抗 |
| 別 名 | Placenta growth factor; PGF; PGFL; PIGF; Placental growth factor vascular endothelial growth factor related protein; PlGF 2; PLGF; PlGF2; PLGF_HUMAN; Vascular endothelial growth factor related protein. |
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Specific References (1) | bsm-54066R has been referenced in 1 publications.
[IF=4.123] Jaiswal P et al. Clinical Proteomics Profiling for Biomarker Identification Among Patients Suffering With Indian Post Kala Azar Dermal Leishmaniasis. Front Cell Infect Microbiol. 2020 May 27;10:251. WB ; Human.
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| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 3F11 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 25 kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | A synthesized peptide derived from human PlGF: 50-100/221 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The placental-derived growth factor (PIGF) is a dimeric glycoprotein showing a high degree of sequence similarity to the vascular endothelial growth factor. Alternative splicing of the PIGF primary transcript gives rise to two forms, named PIGF-1 and PIGF-2, which differ only in the insertion of a highly basic 21-amino acid stretch at the carboxyl end. The presence of the PIGF mRNA in thyroid, placenta, lung, and goiter has indicated the tissues where this factor functions. However, the role of PIGF in vascular development has not yet been clearly established. SWISS: P49763 Gene ID: 5228 PLGF胎盤生長(zhǎng)因子是血管生長(zhǎng)因子家族成員之一（又稱：胎盤型血管內(nèi)皮細(xì)胞生長(zhǎng)因子），是動(dòng)脈粥樣硬化斑塊不穩(wěn)定的主要炎性激活物，因此它可作為ACS患者風(fēng)險(xiǎn)預(yù)測(cè)的生物學(xué)標(biāo)志物.尿胎盤生長(zhǎng)因子水平可預(yù)測(cè)先兆子癇危險(xiǎn).研究人員發(fā)現(xiàn)，在疾病發(fā)作前的6到8周，先兆子癇患者尿液中的胎盤生長(zhǎng)因子水平急劇下降,這種新的尿檢方法使提前1到2個(gè)月預(yù)測(cè)先兆子癇成為可能。亦有研究人員正在從事胎盤生長(zhǎng)因子與肺氣腫，胃癌，腸癌等方面的研究。 |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with PLGF monoclonal antibody, unconjugated (bsm-54066R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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