產(chǎn)品編號 | D62088 |
英文名稱 | CCG-203971 |
中文名稱 | |
別 名 | CCG203971; CCG 203971 |
克 隆 號 | |
CAS | 1443437-74-8 |
理論分子量 | 408.87744 kDa |
檢測分子量 | |
保存條件 | 2-8℃ |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This compound also inhibits PC-3 cell migration (IC50: 4.2 μM), as determined by a scratch wound assay. CCG-203971 causes no cytotoxicity when evaluated by the WST-1 assay. It is well tolerated in normal mice up to doses of 100 mg/kg given intraperitoneally over five days. |