產(chǎn)品編號 | D62125 |
英文名稱 | BMS-1166 |
中文名稱 | |
別 名 | BMS1166 |
克 隆 號 | |
CAS | 1818314-88-3 |
理論分子量 | 641.11 kDa |
檢測分子量 | |
保存條件 | -20℃ |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
BMS-1166 is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation |