產(chǎn)品編號 | D53928 |
英文名稱 | Dehydro Nifedipine |
中文名稱 | 去氫硝苯地平 |
別 名 | BAY-b 4759 |
克 隆 號 | |
CAS | 67035-22-7 |
理論分子量 | 344.32 kDa |
檢測分子量 | |
保存條件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Dehydro Nifedipine is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5. |