| 產(chǎn)品編號(hào) | D58159 |
| 英文名稱(chēng) | SI-2 |
| 中文名稱(chēng) | |
| 別 名 | EPH116 |
| 克 隆 號(hào) | |
| CAS | 223788-33-8 |
| 理論分子量 | 265.31 kDa |
| 檢測(cè)分子量 | |
| 保存條件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1). SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM), but not affect normal cell viability. |
