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Anti-human LAG3 / CD223 (Relatlimab Biosimilar) (BIO0217SM)  
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產(chǎn)品編號(hào) BIO0217SM
英文名稱(chēng) Anti-human LAG3 / CD223 (Relatlimab Biosimilar)
中文名稱(chēng)
抗體來(lái)源
克隆類(lèi)型 Monoclonal
克 隆 號(hào)
交叉反應(yīng) Human,Cynomolgus
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 145.58 kDa
檢測(cè)分子量
性    狀 Lyophilized
亞    型 Human IgG4SP
純化方法 Protein A
保存條件 For long term storage, the produce should be stored at -20°C or lower.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹
產(chǎn)品圖片
Relatlimab inhibited the tumor growth of MC38 on Human LAG3 mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 53.8% at 10 mpk at D28.
Human LAG3 CHO cells were stained with Anti-LAG3 / CD223 Reference Antibody (relatlimab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.5464 ug/mL.
Immobilized human LAG3 His at 2 ug/mL can bind Anti-LAG3 / CD223 Reference Antibody (relatlimab), EC50=0.02812 ug/mL.
The purity of Anti-LAG3 / CD223 Reference Antibody (relatlimab) is 100%, determined by SEC-HPLC.
Anti-LAG3 / CD223 Reference Antibody (relatlimab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
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