| 產(chǎn)品編號(hào) | IHC0545H |
| 英文名稱 | Human Thymidylate synthase Ready-To-Use IHC Kit |
| 中文名稱 | 人胸苷酸合成酶即用型免疫組化試劑盒 |
| 別 名 | HST422; OK/SW-cl.29; TMS; TS; TYMS |
| 克 隆 號(hào) | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Thymidylate Synthase (TS) converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas. SWISS: P04818 Gene ID: 7298 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Human gastric cancer tissue slide using IHC0545H (Human Thymidylate synthase Kit).
Immunohistochemical analysis of paraffin embedded Human ovarian cancer tissue slide using IHC0545H (Human Thymidylate synthase Kit).
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Immunohistochemical analysis of paraffin embedded Human lymph nodes tissue slide using IHC0545H (Human Thymidylate synthase Kit).
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Immunohistochemical analysis of paraffin embedded Human colon cancer tissue slide using IHC0545H (Human Thymidylate synthase Kit).
Immunohistochemical analysis of paraffin embedded Human tonsil tissue slide using IHC0545H (Human Thymidylate synthase Kit).
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