產(chǎn)品編號(hào) | bs-10935R-Gold |
英文名稱(chēng) | Rabbit Anti-CHKL/Gold Conjugated antibody |
中文名稱(chēng) | 膠體金標(biāo)記的乙醇胺激酶β抗體 |
別 名 | Ethanolamine kinase beta; CHETK; Chetk-beta; CHKB; Chkb choline kinase beta; Chkb protein; CHKB_HUMAN; CHKL; Choline kinase beta; Choline kinase-like; Choline kinase-like protein; Choline/ethanolamine kinase; choline/ethanolamine kinase beta; Choline/ethanolamine kinase, beta; CK; CK/EK; CK/EK-beta; CKB; CKEKB; EK; EKB; Ethanolamine kinase; Ethanolamine kinase beta; Ethanolamine kinase, beta. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 45kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CHKL |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Choline kinase (CK) and ethanolamine kinase (EK) catalyzethe phosphorylation of choline/ethanolamine tophosphocholine/phosphoethanolamine. This is the first enzyme in thebiosynthesis of phosphatidylcholine/phosphatidylethanolamine in allanimal cells. The highly purified CKs from mammalian sources andtheir recombinant gene products have been shown to have EK activityalso, indicating that both activities reside on the same protein.The choline kinase-like protein encoded by CHKL belongs to thecholine/ethanolamine kinase family; however, its exact function isnot known. Read-through transcripts are expressed from this locusthat include exons from the downstream CPT1B locus. [provided byRefSeq, Jun 2009]. Function: Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis. Subunit: Homodimer, and heterodimer with CHKA. Similarity: Belongs to the choline/ethanolamine kinase family. Database links: Entrez Gene: 1120 Human Omim: 612395 Human SwissProt: Q9Y259 Human Unigene: 654827 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |