| 產(chǎn)品編號(hào) | bs-18047R-Cy5.5 |
| 英文名稱 | Rabbit Anti-HMBOX1/Cy5.5 Conjugated antibody |
| 中文名稱 | Cy5.5標(biāo)記的HMBOX1蛋白抗體 |
| 別 名 | FLJ21616; HMBOX1; HMBOX1A; HMBX1_HUMAN; HNF1LA; homeobox containing 1; Homeobox containing protein 1; Homeobox-containing protein 1; homeobox-containing protein PBHNF; PBHNF. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 47kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HMBOX1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: HMBOX1 is a 420 amino acid nuclear protein that contains one homeobox DNA-binding domain and is thought to function as a putative transcription factor. HMBOX1 is expressed as three alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 8. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8. Function: Transcription factor. Isoform 1 acts as a transcriptional repressor. Isoform 4 has very low activity as a transcriptional repressor. Subcellular Location: Nucleus. Cytoplasm. Predominantly detected in cytoplasm. Tissue Specificity: Ubiquitous. Detected in pancreas, brain, spleen, placenta, prostate, thymus, liver, heart, bone marrow, skeletal muscle, stomach, uterus, testis, kidney, ovary, and colon. Similarity: Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 79618 Human Entrez Gene: 219150 Mouse SwissProt: Q6NT76 Human SwissProt: Q8BJA3 Mouse Unigene: 591836 Human Unigene: 344074 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
