| 產(chǎn)品編號 | bs-17643R-Gold |
| 英文名稱 | Rabbit Anti-SPCS3/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的信號肽復(fù)合物亞基3抗體 |
| 別 名 | DKFZp564J1864; FLJ22649; Microsomal signal peptidase 22/23 kDa subunit; Microsomal signal peptidase 23 kDa subunit; PRO3567; Signal peptidase complex subunit 3; Signal peptidase complex subunit 3 homolog (S. cerevisiae); Signal peptidase complex subunit 3 homolog; SPase 22 kDa subunit; SPase 22/23 kDa subunit; SPC22; SPC22/23; SPC3; UNQ1841; YLR066W. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 20kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SPCS3 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: SPCS3 (signal peptidase complex subunit 3), also known as SPC3, is a 180 amino acid single-pass type II membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER) and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS3 functions to remove signal peptides from proteins that are translated to the lumen of the ER. The gene encoding SPCS3 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Function: A component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Subunit: Component of the microsomal signal peptidase complex which consists of five members: SEC11A, SEC11C, SPCS1, SPCS2 and SPCS3. Subcellular Location: Endoplasmic reticulum and Microsome membrane;: Single-pass type II membrane protein Similarity: Belongs to the SPCS3 family. Database links: Entrez Gene: 60559 Human Entrez Gene: 76219 Mouse Entrez Gene: 76976 Mouse SwissProt: P61009 Human SwissProt: Q9D365 Mouse Unigene: 6322 Cow Unigene: 3875 Dog Unigene: 42194 Human Unigene: 328305 Mouse Unigene: 482965 Mouse Unigene: 162344 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
