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Rabbit Anti-PARP14/Cy7 Conjugated antibody (bs-19886R-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19886R-Cy7
英文名稱 Rabbit Anti-PARP14/Cy7 Conjugated antibody
中文名稱 Cy7標(biāo)記的多腺苷二磷酸多聚酶PARP14抗體
別    名 ADP-ribosyltransferase diphtheria toxin-like 8; ARTD8; B aggressive lymphoma protein 2; BAL2; Collaborator of STAT6; KIAA1268; PAR14_HUMAN; PARP 14; PARP-14; PARP14; pART8; Poly (ADP ribose) polymerase family member 14; Poly [ADP-ribose] polymerase 14.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 203kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PARP14
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent posttranslational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP14 belongs to the superfamily of enzymes that perform this modification (Ame et al., 2004 [PubMed 15273990]).[supplied by OMIM, Mar 2008]

Function:
Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.

Subunit:
Interacts with STAT6.

Subcellular Location:
Nucleus. Cytoplasm. In steady state cells the protein is mostly nuclear. A minor proportion is detected in the cytoplasm.

Similarity:
Contains 3 Macro domains.
Contains 1 PARP catalytic domain.
Contains 1 WWE domain.

Database links:

Entrez Gene: 54625 Human

Entrez Gene: 547253 Mouse

Entrez Gene: 303903 Rat

Omim: 610028 Human

SwissProt: Q460N5 Human

SwissProt: Q2EMV9 Mouse

Unigene: 518203 Human

Unigene: 244406 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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