| 產(chǎn)品編號 | bs-19700R-FITC |
| 英文名稱 | Rabbit Anti-QTRTD1/FITC Conjugated antibody |
| 中文名稱 | FITC標(biāo)記的轉(zhuǎn)運RNA核糖轉(zhuǎn)移酶結(jié)構(gòu)域蛋白QTRTD1抗體 |
| 別 名 | FLJ12960; QTRD1_HUMAN; qtrtd1; queuine tRNA ribosyltransferase domain containing 1; Queuine tRNA-ribosyltransferase domain-containing protein 1; Queuine tRNA-ribosyltransferase subunit qtrtd1. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細胞生物 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, (predicted: Rat, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 47kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human QTRTD1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012] Function: Interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Subunit: Interacts with QTRT1. Subcellular Location: Cytoplasm. Mitochondrion. May associate with the mitochondrion outer membrane. Similarity: Belongs to the queuine tRNA-ribosyltransferase family. QTRTD1 subfamily. Database links: Entrez Gene: 79691 Human Entrez Gene: 106248 Mouse SwissProt: Q9H974 Human SwissProt: B8ZXI1 Mouse Unigene: 477162 Human Unigene: 275354 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
