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Rabbit Anti-QTRTD1/PE-Cy3 Conjugated antibody (bs-19700R-PE-Cy3)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-19700R-PE-Cy3
英文名稱 Rabbit Anti-QTRTD1/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的轉(zhuǎn)運(yùn)RNA核糖轉(zhuǎn)移酶結(jié)構(gòu)域蛋白QTRTD1抗體
別    名 FLJ12960; QTRD1_HUMAN; qtrtd1; queuine tRNA ribosyltransferase domain containing 1; Queuine tRNA-ribosyltransferase domain-containing protein 1; Queuine tRNA-ribosyltransferase subunit qtrtd1.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human QTRTD1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

Function:
Interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

Subunit:
Interacts with QTRT1.

Subcellular Location:
Cytoplasm. Mitochondrion. May associate with the mitochondrion outer membrane.

Similarity:
Belongs to the queuine tRNA-ribosyltransferase family. QTRTD1 subfamily.

Database links:

Entrez Gene: 508374 Cow

Entrez Gene: 79691 Human

Entrez Gene: 106248 Mouse

Entrez Gene: 288364 Rat

SwissProt: Q9H974 Human

SwissProt: B8ZXI1 Mouse

Unigene: 477162 Human

Unigene: 275354 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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